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Estimation of load and resistance factors using the third-moment method based on the 3P-lognormal distribution

Yan-Gang ZHAO, Zhao-Hui LU

Frontiers of Structural and Civil Engineering 2011, Volume 5, Issue 3,   Pages 315-322 doi: 10.1007/s11709-011-0117-7

Abstract: Load and resistance factors are generally obtained using the first order reliability method (FORM) inA simple method based on the third-moment method for estimating load and resistance factors is then proposed, and a simple formula for the target mean resistance is also presented to avoid iterative computationsUnlike the currently used method, the proposed method can be used to determine load and resistance factorsThus, the method provides a more convenient and effective way to estimate load and resistance factors

Keywords： load and resistance factors     third-moment method     three-parameter lognormal (3P-lognormal) distribution     target mean resistance     simple formula    

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High-order moment methods for LRFD including random variables with unknown probability distributions

Zhao-Hui LU, Yan-Gang ZHAO, Zhi-Wu YU

Frontiers of Structural and Civil Engineering 2013, Volume 7, Issue 3,   Pages 288-295 doi: 10.1007/s11709-013-0210-1

Abstract: The reliability-based load and resistance factors design (LRFD) has been widely used in the structuralIn almost all of the current reliability methods for the determination of the load and resistance factorsFrom the investigation of the present paper, it can be concluded that: 1) The load and resistance factorsproposed method may be different from those obtained by first order reliability method (FORM), the targetmean resistances obtained by both methods are essentially the same.

Keywords： high-order moment methods     applicable range     load and resistance factors     target mean resistance    

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mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?

Shi-Yong Sun

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 221-231 doi: 10.1007/s11684-020-0812-7

Abstract: The mammalian target of rapamycin (mTOR) critically regulates several essential biological functions,signaling is often dysregulated in cancers and has been considered an attractive cancer therapeutic target

Keywords： mTOR     cancer therapy     resistance     GSK3     protein degradation     E3 ubiquitin ligase     PD-L1    

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Calculations of narrow-band transimissities and the Planck mean absorption coefficients of real gases

Huaqiang CHU, Mingyan GU, Huaichun ZHOU, Fengshan LIU

Frontiers in Energy 2014, Volume 8, Issue 1,   Pages 41-48 doi: 10.1007/s11708-013-0292-4

Abstract: The Planck mean absorption coefficients of CO , H O, CO, and CH in the temperature range of 300 to 2500The SNB model was also used to calculate the Planck mean absorption coefficients of these four radiatingThe LBL results of the Planck mean absorption coefficient were compared with the classical results of

Keywords： transimissity     HITEMP     HITRAN     Planck mean absorption coefficients    

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A job-insertion heuristic for minimizing the mean flowtime in dynamic flowshops

Guang GUO, Bo WU, Shuzi YANG

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 2,   Pages 197-202 doi: 10.1007/s11465-011-0211-5

Abstract:

A new adaptive job-insertion based heuristic is presented to minimize the mean flowtime in a dynamicthan the SPT dispatching rule, which is currently one of the most effective methods for minimizing the mean

Keywords： scheduling     dynamic flowshops     flowtime     heuristic     mean flowtime    

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Theoretical prediction and validation of global horizontal solar irradiance for a tropical climate in India

Sivasankari SUNDARAM,Jakka SARAT CHANDRA BABU

Frontiers in Energy 2015, Volume 9, Issue 3,   Pages 311-321 doi: 10.1007/s11708-015-0369-3

Abstract: The proposed regression models were validated by the significance of statistical indicators such as meanbias error, root mean square error and mean percentage error from the predicted and the actual values

Keywords： global horizontal irradiance (GHI)     mean bias error     root mean square error     mean percentage error     coefficient    

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Some remarks on the engineering application of the fatigue crack growth approach under nonzero mean loads

Jorge Alberto Rodriguez DURAN,Ronney Mancebo BOLOY,Rafael Raider LEONI

Frontiers of Mechanical Engineering 2015, Volume 10, Issue 3,   Pages 255-262 doi: 10.1007/s11465-015-0342-1

Abstract:

The well-known fatigue crack growth (FCG) curves are two-parameter dependents. The range of the stress intensity factor ?K and the load ratio R are the parameters normally used for describing these curves. For engineering purposes, the mathematical representation of these curves should be integrated between the initial and final crack sizes in order to obtain the safety factors for stresses and life. First of all, it is necessary to reduce the dependence of the FCG curves to only one parameter. ?K is almost always selected and, in these conditions, considered as the crack driving force. Using experimental data from literature, the present paper shows how to perform multiple regression analyses using the traditional Walker approach and the more recent unified approach. The correlations so obtained are graphically analyzed in three dimensions. Numerical examples of crack growth analysis for cracks growing under nominal stresses of constant amplitude in smooth and notched geometries are performed, assuming an identical material component as that of the available experimental data. The resulting curves of crack size versus number of cycles (a vs. N) are then compared. The two models give approximately the same (a vs. N) curves in both geometries. Differences between the behaviors of the (avs. N) curves in smooth and notched geometries are highlighted, and the reasons for these particular behaviors are discussed.

Keywords： fatigue crack propagation modeling     life prediction     mean stress effects    

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Observer design for induction motor: an approach based on the mean value theorem

Mohamed Yacine HAMMOUDI,Abdelkarim ALLAG,Mohamed BECHERIF,Mohamed BENBOUZID,Hamza ALLOUI

Frontiers in Energy 2014, Volume 8, Issue 4,   Pages 426-433 doi: 10.1007/s11708-014-0314-x

Abstract: dynamics for the induction motor into the linear parametric varying (LPV) system, the differential mean

Keywords： observer design     differential mean value theorem (DMVT)     sector nonlinearity transformation     linear matrix    

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Mean wind load induced incompatibility in nonlinear aeroelastic simulations of bridge spans

Zhitian ZHANG

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 3,   Pages 605-617 doi: 10.1007/s11709-018-0499-x

Abstract: Mean wind response induced incompatibility and nonlinearity in bridge aerodynamics is discussed, wherethe mean wind and aeroelastic loads are applied simultaneously in time domain.A kind of incompatibility is found during the simultaneous simulation of the mean wind and aeroelasticloads, which leads to incorrect mean wind structural responses.leads to incorrect mean responses due to its nonphysical mean properties.

Keywords： bridge     aerodynamics     nonlinear     aeroelastic model     Pseudo-steady     mean wind loads    

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Multi-target combinatory strategy to overcome tumor immune escape

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 208-215 doi: 10.1007/s11684-022-0922-5

Abstract: The use of several antibody drugs that target PD1/PD-L1 for various cancer treatments has been approvedApproximately 80% of patients do not respond appropriately because of primary or acquired therapeutic resistance

Keywords： immune checkpoints     multi-target     immune escape     immune-related adverse events     combination therapy    

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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: A long-held belief is that pituitary hormones bind to their cognate receptors in classical target glandshave shown that multiple types of pituitary hormone receptors are widely expressed in non-classical targetgland-derived hormone exhibits a wide range of nonconventional biological effects in these non-classical targetnon-classical organs were summarized, defined by the novel concept of an “atypical pituitary hormone–targetThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” could

Keywords： thyroid-stimulating hormone     follicle-stimulating hormone     luteinizing hormone     adrenocorticotrophic hormone     prolactin    

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Classical state feedback controller for nonlinear systems using mean value theorem: closed loop-FOC of

Abrar ALLAG,Abdelhamid BENAKCHA,Meriem ALLAG,Ismail ZEIN,Mohamed Yacine AYAD

Frontiers in Energy 2015, Volume 9, Issue 4,   Pages 413-425 doi: 10.1007/s11708-015-0379-1

Abstract: A simple systematic and useful synthesis method is proposed based on the use of the differential meanThe proposed design approach is based on the mean value theorem (MVT) to express the nonlinear error

Keywords： systems     sector nonlinearity     nonlinear controller     linear matrix inequality (LMI) approach     differential mean    

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Protein phosphatase magnesium-dependent 1δ is a novel tumor marker and target in hepatocellular carcinoma

Zhi Xu,Chunxiang Cao,Haiyan Xia,Shujing Shi,Lingzhi Hong,Xiaowei Wei,Dongying Gu,Jianmin Bian,Zijun Liu,Wenbin Huang,Yixin Zhang,Song He,Nikki Pui-Yue Lee,Jinfei Chen

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 52-60 doi: 10.1007/s11684-016-0433-3

Abstract:  Overall, results suggest that PPM1D is a potential prognostic marker and therapeutic target

Keywords： PPM1D     hepatocellular carcinoma     prognosis     target therapy    

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Amodified variable rate particle filter for maneuvering target tracking

Yun-fei GUO,Kong-shuai FAN,Dong-liang PENG,Ji-an LUO,Han SHENTU

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 11,   Pages 985-994 doi: 10.1631/FITEE.1500149

Abstract: To address the problem of maneuvering target tracking, where the target trajectory has prolonged smoothCompared with conventional variable rate models, the proposed model does not need any prior knowledge of target

Keywords： Maneuvering target tracking     Prolonged smooth regions     Variable rate model     Maneuver detection    

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Prevalence of antifolate drug resistance markers in in China

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 83-92 doi: 10.1007/s11684-021-0894-x

Abstract: dhfr) and dihydropteroate synthetase (dhps) genes of Plasmodium vivax and antifolate resistance-associatedgenes were used for drug resistance surveillance.This study indicated that the antifolate resistance levels of P. vivax parasites were differentacross China and molecular markers could be used to rapidly monitor drug resistance.

Keywords： drug resistance     antifolates     molecular markers     Plasmodium vivax     China    

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Title Author Date Type Operation

Estimation of load and resistance factors using the third-moment method based on the 3P-lognormal distribution

Yan-Gang ZHAO, Zhao-Hui LU

Journal Article

High-order moment methods for LRFD including random variables with unknown probability distributions

Zhao-Hui LU, Yan-Gang ZHAO, Zhi-Wu YU

Journal Article

mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?

Shi-Yong Sun

Journal Article

Calculations of narrow-band transimissities and the Planck mean absorption coefficients of real gases

Huaqiang CHU, Mingyan GU, Huaichun ZHOU, Fengshan LIU

Journal Article

A job-insertion heuristic for minimizing the mean flowtime in dynamic flowshops

Guang GUO, Bo WU, Shuzi YANG

Journal Article

Theoretical prediction and validation of global horizontal solar irradiance for a tropical climate in India

Sivasankari SUNDARAM,Jakka SARAT CHANDRA BABU

Journal Article

Some remarks on the engineering application of the fatigue crack growth approach under nonzero mean loads

Jorge Alberto Rodriguez DURAN,Ronney Mancebo BOLOY,Rafael Raider LEONI

Journal Article

Observer design for induction motor: an approach based on the mean value theorem

Mohamed Yacine HAMMOUDI,Abdelkarim ALLAG,Mohamed BECHERIF,Mohamed BENBOUZID,Hamza ALLOUI

Journal Article

Mean wind load induced incompatibility in nonlinear aeroelastic simulations of bridge spans

Zhitian ZHANG

Journal Article

Multi-target combinatory strategy to overcome tumor immune escape

Journal Article

Atypical pituitary hormone–target tissue axis

Journal Article

Classical state feedback controller for nonlinear systems using mean value theorem: closed loop-FOC of

Abrar ALLAG,Abdelhamid BENAKCHA,Meriem ALLAG,Ismail ZEIN,Mohamed Yacine AYAD

Journal Article

Protein phosphatase magnesium-dependent 1δ is a novel tumor marker and target in hepatocellular carcinoma

Zhi Xu,Chunxiang Cao,Haiyan Xia,Shujing Shi,Lingzhi Hong,Xiaowei Wei,Dongying Gu,Jianmin Bian,Zijun Liu,Wenbin Huang,Yixin Zhang,Song He,Nikki Pui-Yue Lee,Jinfei Chen

Journal Article

Amodified variable rate particle filter for maneuvering target tracking

Yun-fei GUO,Kong-shuai FAN,Dong-liang PENG,Ji-an LUO,Han SHENTU

Journal Article

Prevalence of antifolate drug resistance markers in in China

Journal Article